Garcia-Diez I, et al. - Authors evaluated the clinical and immunological features of patients with pemphigoid induced by dipeptidyl peptidase-4 (DPP-4) inhibitors. An inflammatory or a noninflammatory phenotype of BP could be presented by patients with DPP-4 inhibitor-induced BP. Findings suggested the pathogenic relevance of IgG response against other BP180 regions different from the NC16A domain, such as LAD-1 and the C-terminal domain, to the onset of DPP-4 inhibitor-induced BP. Authors noted that most patients reacted to more than 1 BP180 antigenic site (LAD-1 and/or C-terminal domain) on the immunoblot.