Sastre B, García‐García ML, Cañas JA, et al. - Researchers assessed the innate immune response that characterizes bronchiolitis (BCH) and recurrent wheezing (RW). This study involved 98 and 70 hospitalized infants who received a diagnosis of BCH or RW, respectively. Higher ILC2 (type 2 innate lymphoid cells) percentage was detected in bronchiolitis patients vs RW. Significantly raised TLR3 , IL33 , IFNG , IL10 , and FLG mRNA levels were also detected in BCH vs RW. Findings revealed a link of bronchiolitis with raised nasal percentage of ILC2. This cellular population could represent the crucial component in the differential immune response between BCH and RW which share some mechanisms such us monocyte activation, vascular damage, and fibroblast repair. A likely role of lipid mediators in the evolution of the disease later in life, via innate lymphoid cells, was suggested.