Breastfeeding factors and risk of epithelial ovarian cancer
Gynecologic Oncology Jan 31, 2019
Modugno F, et al. - In this population-based, case-control study conducted in Pennsylvania, Ohio, and New York from 2003 to 2008, researchers analyzed the correlation between breastfeeding characteristics and epithelial ovarian cancer (EOC). Using multivariable unconditional logistic regression, breastfeeding factors were examined among parous women. Six hundred eighty-nine incident EOC cases were compared to 1,572 community controls. Breastfeeding any offspring was related to a 30% reduction in EOC risk vs never breastfeeding. Overall, investigators concluded that breastfeeding for as little as 3 months was linked to reduced EOC risk. While this association decreases over time, it endures for more than 30 years. They observed that longer cumulative duration, increasing number of breastfeeding episodes, and earlier age at first breastfeeding episode were each related to increased benefit.
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