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Breast-conserving surgery followed by whole-breast irradiation offers survival benefits over mastectomy without irradiation

British Journal of Surgery Jun 25, 2018

de Boniface J, et al. - Considering recent retrospective analyses that have suggested a survival benefit for less extensive breast surgery, researchers sought to gain evidence for the links of such survival data with locoregional recurrence rates. They prospectively included clinically node-negative patients with breast cancer who had planned sentinel node biopsy between 2000 and 2004 in the Swedish Multicentre Cohort Study. Breast-conserving surgery with postoperative radiotherapy was noted to be superior over mastectomy without radiotherapy. Significant differences regarding the axillary recurrence rate were noted, and that could be one contributing factor in a complex explanatory model.

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