Radziunas A, et al. - Whether cortical and subcortical volume and cortical thickness has any connection with sleep disturbances in patients with Parkinson disease (PD) was evaluated. For this investigation, 28 PD subjects were assessed for sleep disturbances with the Parkinson’s disease Sleep Scale and had a brain MRI. Automated voxel based image analysis was carried out using the FreeSurfer software. Prominent basal ganglia volume reduction was found in PD patients with nocturnal hallucinations. Researchers reported that distressful dreams were correlated with a limbic system and frontal white matter changes. Findings also revealed that nocturia was mostly linked with global white matter reduction and surface reduction of a cortical surface on the left hemisphere pre- and postcentral areas.