Shan ZY, et al. - Researchers assessed the temporal complexity of blood oxygenation level dependent (BOLD) changes in response to the Stroop task in chronic fatigue syndrome (CFS) patients using quantitative magnetic resonance imaging (MRI). Patients’ mental component summary (MCS) and physical component summary (PCS) from the 36-item Short Form Health Survey (SF-36) questionnaire were recorded. In CFS patients, BOLD SampEn in ten regions were significantly lower.Iin patients with CFS, the brain appeared to respond differently to a cognitive challenge, and seemed to recruit wider regions to compensate for lower information capacity.