Kwon SY, Chun KJ, Kil HK, et al. - In the present study, the researchers sought to assess the clinical effectiveness and safety of botulinum toxin (BTX) injection and to further analyze its impact on parotid gland function and volume utilizing salivary single‐photon emission computed tomography (SPECT)‐computed tomography (CT). BTX injections into the parotid glands were given to 14 patients with chronic parotitis. Pain, postprandial pain, swelling, aesthetic discomfort, and salivary flow rate have been evaluated before injection, at 2 weeks, and at 1, 3, and 6 months. According to results, all subjective symptoms reduced significantly until 1 month and then increased, however, at 6 months, all subjective symptoms were determined to be better than before the injection. A substantial difference over time was not shown in the unstimulated and stimulated salivary flow rate. No major difference was observed in parotid gland volume or uptake on salivary SPECT–CT over time. An alternative treatment choice for chronic parotitis could be the BTX injection.