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Bone mineral density in emphysema and chronic bronchitis phenotypes in hospitalized male COPD patients

The Clinical Respiratory Journal Oct 24, 2019

Yormaz B, et al. - Since an increased risk of osteoporosis in COPD is normally overlooked, particularly in male patients, therefore, researchers compared male COPD patients with emphysema and the chronic bronchitis phenotype with respect to bone mineral density (BMD) measurements, and they assessed the link between density of emphysema and osteoporosis. In this prospective analysis, they analyzed 94 patients with COPD, and with emphysema and the chronic bronchitis phenotype. Among patients with emphysema and bronchitis, osteoporosis was present in 60.47% and 17.65% and osteopenia was found in 27.91% and 41.18% of patients, respectively. In patients with osteoporosis, high resolution computed tomography emphysema density was negatively correlated with bone densitometer t-score, and BMI was positively correlated with the bone densitometer t-score. Independent risk factors for a low BMD were BMI and emphysema score. Experts recommended assessment for osteoporosis in particularly male patients with emphysema, high dyspnea score, low BMI and frequent exacerbations.
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