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Bone mineral density in diabetes and impaired fasting glucose

Osteoporosis International Sep 06, 2019

Holloway-Kew KL, et al. - Women (n = 858) and men (n = 970) who were aged 20–80 years, from the Geelong Osteoporosis Study, were involved in order to ascertain whether individuals with impaired fasting glucose (IFG) have increased or normal BMD. No correlations between glycaemic status and BMD for premenopausal women were found. For non-obese postmenopausal women, there was no relationship between femoral neck BMD (FNBMD) and glycaemic status, though women with IFG or diabetes had greater lumbar spine BMD (LSBMD) in comparison with those with normoglycaemia. Obese postmenopausal women with diabetes had a higher FNBMD and LSBMD, however, those with IFG were not distinctive from the normoglycaemia group. No correlations were identified between glycaemic status and BMD in men. Thus, it was reported that, in comparison with normoglycaemia, postmenopausal women (non-obese and obese) with diabetes had greater LSBMD. In obese postmenopausal women with diabetes, FNBMD was greater. Only non-obese postmenopausal women with IFG had a higher LSBMD vs normoglycaemia. No other relationships with IFG were noted.
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