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Bone marrow-derived mononuclear cell therapy for nonischaemic dilated cardiomyopathy - A meta-analysis

European Journal of Clinical Investigation May 01, 2018

Wen Y, et al. - Researchers gauged the effects of bone marrow-derived mononuclear cells (BMMNCs) transplantation on left ventricular ejection fraction (LVEF) in patients with non-ischemic dilated cardiomyopathy (DCM). Findings revealed that, compared to the use of G-CSF-stimulated bone marrow/peripheral blood stem cells, BMMNCs were more effective in improving LVEF in patients with non-ischemic DCM. Data shed light on the connection between BMMNCs transplantation with a moderate, yet significant, improvement in LVEF in patients with non-ischemic DCM.

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