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Body weight and eGFR during dulaglutide treatment in type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7)

Diabetes, Obesity and Metabolism Mar 20, 2019

Tuttle KR, et al. - In this investigation, researchers studied whether reduced eGFR decline with dulaglutide is related to body weight (BW) loss. According to this post hoc analysis, BW decreased with dulaglutide 1.5 mg and 0.75 mg and increased with insulin glargine. Moreover, changes in eGFR were not significant with dulaglutide 1.5 mg and 0.75 mg. However, eGFR significantly decreased with insulin glargine. Findings suggested that BW loss was not affected by a lower decline in eGFR observed with dulaglutide.

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