Dusingize JC, Olsen CM, An J, et al. - Given both height and body mass index (BMI) have been positively related to melanoma risk, although less consistent findings have been generated for BMI than height, and there is a lack of clarity regarding if these links indicate causality or are because of residual confounding by environmental and lifestyle risk factors, so, researchers re-assessed these links employing a two-sample Mendelian randomization approach. They utilized separate genome-wide association study (GWAS) meta-analyses in order to identify single nucleotide polymorphisms (SNPs) for BMI and height. Using the most recent melanoma GWAS meta-analysis including 12,874 cases and 23,203 controls, melanoma SNPs were obtained. Experts gained no proof for a causal link between higher BMI and melanoma, however, the findings lend support to the idea that height is causally related to melanoma risk. No clarity was gained about the mechanisms by which height impacts melanoma risk, and it is likely that the effect could be mediated via diverse pathways including growth factors and even socioeconomic status.