Zhou C, Jin L, Wang Q, et al. - Researchers examined 208 patients with carbapenem-resistant Enterobacterales bloodstream infections (CRE BSIs) from 18 hospitals across nine Chinese provinces with the aim to determine the risk factors for mortality and describe potential treatment options for CRE infection. Among these patients, the overall 30-day mortality rate of 46.2% was identified. Carbapenem-resistant Klebsiella pneumoniae (CRKP) was identified as the causative pathogen (85.6%). They recorded a high sepsis/septic shock incidence rate for patients infected by ST11-KL64 CRKP. Risk factors independently linked with mortality were: sepsis/septic shock, short duration of antimicrobial therapy and empirical using tigecycline were independent. Better survival benefit was observed in correlation with appropriate therapy vs inappropriate therapy. Based on findings, they emphasize comprehensively considering whether the antimicrobials were used appropriately, together with infection severity and CRE strains, in order to lower the mortality of CRE BSIs .