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Blood type as a predictor of high-grade dysplasia and associated malignancy in patients with intraductal papillary mucinous neoplasms

Journal of Gastrointestinal Surgery Sep 08, 2018

Poruk KE, et al. - Researchers reviewed the medical records of all patients undergoing resection of an intraductal papillary mucinous neoplasm (IPMN) at Johns Hopkins Hospital from June 1997 to August 2016 to assess if non-O blood types are more commonly seen in patients with IPMNs and if blood type is a risk factor for progression to invasive pancreatic cancer among patients with IPMN. In this work, non-O blood types were observed more frequently among IPMN patients than controls, but type O blood carriers had higher odds of having high-grade dysplasia in their IPMN. Results thereby suggest a possible impact of blood type on the risk and progression of IPMNs.

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