Roumie CL, Hung AM, Russell GB, et al. - In light of previous study findings of reduced cardiovascular outcomes in the Systolic Blood Pressure Intervention Trial, researchers investigated the incidence of diabetes mellitus in relation to intensive blood pressure strategy (systolic blood pressure < 120 mm Hg) vs standard strategy (< 140 mm Hg) in a randomized trial. The study sample comprised adults aged 50 and older who had systolic blood pressure levels of 130 to 180 mmHg and increased cardiovascular risk. The researchers identified 299 incident diabetes mellitus events (2.3% per year) for intensive and 251 events (1.9% per year) for standard, rates of 22.6 (20.2–25.3) compared with 19.0 (16.8–21.5) events per 1,000 person-years of treatment, respectively (adjusted HR: 1.19 [95% CI: 0.95–1.49]). Overall, there was no connection between intensive treatment strategy and increased risk of diabetes mellitus. However, there was an association with more impaired fasting glucose. Experts recommended considering the risks and benefits of intensive blood pressure targets when developing individualized patient treatment goals.