Christakoudi S, et al. - Researchers assessed the risk of cancer development at all anatomical sites in relation to systolic (SBP) and diastolic (DBP) blood pressure levels in a sample from the European Prospective Investigation into Cancer and Nutrition. Participants included 307,318 men and women who were followed-up for an average of 13.7 years. Overall, they identified 39,298 incident cancers. The expected positive link with renal cell carcinoma was corroborated (HR: 1.12 [1.08-1.17] per 10 mmHg higher SBP; HR: 1.23 [1.14-1.32] for DBP). For esophageal squamous cell carcinoma (SCC), positive links were identified (HR:1.16 for SBP; HR:1.31 for DBP). Weaker links were reported for head and neck cancers (HR: 1.08 for SBP; HR: 1.09 for DBP) and, similarly, for skin SCC, colon cancer, post-menopausal breast cancer, and uterine adenocarcinoma (AC)—but not for esophageal AC, lung SCC, lung AC, or uterine endometroid cancer. In addition, weak inverse associations of SBP with cervical SCC and lymphomas were also found. For cancers in other locations, no consistent links were identified. In this study, weak links between blood pressure and cancers in particular locations and morphologies were supported.