Nordenstam F, et al. - Researchers investigated if exclusive prenatal exposure to nicotine from maternal use of smokeless tobacco (Swedish snus) in pregnancy was related to blood pressure and autonomic heart rate control in their children. This study included forty 5- to 6-year-old children with snus exposure in fetal life (n = 21) and tobacco-free controls (n = 19), in whom, oscillometric blood pressures were recorded. Findings revealed higher systolic blood pressure and altered heart rate variability at 6 years of age in correlation with prenatal snus exposure. Adverse prenatal programming of nicotine may be suggested by the findings but implications for cardiovascular health in later life remain to be examined. Meanwhile, avoiding all types of tobacco and nicotine products during pregnancy should be advised to women.