Nordenstam F, et al. - Researchers investigated the link of exclusive prenatal exposure to nicotine from maternal use of smokeless tobacco (Swedish snus) in pregnancy, with blood pressure and autonomic heart rate control in their children. In forty 5- to 6-year-old children with snus exposure in fetal life (n = 21) and in tobacco-free controls (n = 19), the oscillometric blood pressures were measured. Findings revealed higher systolic blood pressure and altered heart rate variability at 6 years of age in correlation with prenatal snus exposure. Adverse prenatal programming of nicotine may be suggested by these results, however, implications for cardiovascular health in later life remain unexamined. Meanwhile, avoiding all types of tobacco and nicotine products during pregnancy should be advised to women.