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Blood eosinophil count correlates with severity of respiratory failure in life-threatening asthma and predicts risk of subsequent exacerbations

Clinical & Experimental Allergy Aug 25, 2019

Yii ACA, Tay TR, Puah SH, et al. - Researchers retrospectively reviewed all life-threatening asthma cases admitted at 4 public hospitals in Singapore from 2011 to 2015, to examine the link between a spot blood eosinophil count, measured at the onset of a life-threatening asthma exacerbation, with indices of exacerbation severity and risk of subsequent exacerbations. In this study, 329 survivors were observed over a median duration of 52 months. In those, an increased hazard of emergency visits and/or admissions for asthma was observed in relation to blood eosinophils ≥ 1.200 × 109/L. Findings revealed a correlation between a spot blood eosinophil count and the severity of respiratory failure in this study of life-threatening asthma. Additionally, the risk of subsequent exacerbations was predicted by a spot blood eosinophil count.
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