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Blood acetylcholinesterase activity is associated with increased 10 year all-cause mortality following coronary angiography

Atherosclerosis Oct 13, 2020

Shenhar-Tsarfaty S, Brzezinski RY, Waiskopf N, et al. - Whether serum cholinesterase activity can enable the prediction of long term survival in patients undergoing coronary angiography, was examined in this study. Researchers prospectively observed a total of 1,002 consecutive patients receiving clinically indicated coronary angiography (acute coronary syndrome or stable angina). The acetylcholine analog acetylthiocholine was used to determine blood acetylcholinesterase (AChE) activity. Over 10 years of follow-up, death rates were ascertained. Findings revealed that a raised risk for mortality was observed during long-term follow-up in patients presenting for coronary angiography with low levels of serum AChE activity.

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