Hetzel J, et al. - Including patients with interstitial lung disease (n=359) needing diagnostic bronchoscopic tissue sampling, this study was undertaken to determine the risk of bleeding of transbronchial cryobiopsy vs transbronchial forceps biopsy. For each intervention, researchers assessed bleeding severity semi-quantitatively as “no bleeding”, “mild” (suction alone), “moderate” (additional intervention) or “severe” (prolonged monitoring necessary or fatal outcome). Total patients were 359, with 1160 cryobiopsies and 1302 forceps biopsies done. A clinically relevant increased risk of bleeding was reported in relation to transbronchial cryobiopsy vs transbronchial forceps biopsy, and thus, bleeding control via training and additional precautions was recommended.