Vielmuth F, et al. – The objectives of this study are to assess the rigidity of the human internal limiting membrane (MLI) and to assess possible changes in mechanical properties after intravitreal injection of ocriplasmin to treat vitreomacular traction. Intravitreal injections of ocriplasmin do not change the biomechanical properties of human MLI. There is no evidence of a possible enzymatic impact that interferes with the stiffness of this basement membrane.