Christensen CH, Chang JT, Rostron BL, et al. - Studies suggest detection of lower concentrations of biomarkers of tobacco toxicant exposure among former smokers who currently use e-cigarettes vs current smokers. Researchers sought to determine if tobacco toxicant exposure reductions may result in health risk reductions. Findings revealed greater concentration of F2-isoprostane in dual users vs smokers. Among 3,712 adult participants in Wave 1 (2013-2014) of the Population Assessment of Tobacco and Health Study, inflammatory biomarkers (high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), fibrinogen, soluble intercellular adhesion molecule-1 (sICAM-1)) and an oxidative stress marker (F2-isoprostane) were compared by tobacco user groups: dual users of cigarettes and e-cigarettes; former smokers who currently use e-cigarettes-only; current cigarette-only smokers; former smokers who do not currently use any tobacco; and never tobacco users. Per findings, biomarker concentrations in exclusive e-cigarette users were similar to those of former smokers who do not currently use tobacco, and were lower than those of exclusive cigarette smokers.