Maalmi H, Herder C, Strassburger K, et al. - In this investigation involving 165 people with type 1 diabetes and 291 with type 2 diabetes, researchers sought to explore cross-sectional and prospective connections between biomarkers of inflammation and kidney function in recent-onset diabetes. The sample consisted of people with type 1 and type 2 diabetes with known diabetes duration of <1 year from the German Diabetes Study. According to results, baseline eGFR was higher in type 1 vs type 2 diabetes (102 ± 15 vs 90 ± 16 mL/min/1.73 m²). After full adjustment for covariates and multiple testing, 7 biomarkers were correlated with lower baseline eGFR in type 1 diabetes and 24 were related to lower baseline eGFR in type 2 diabetes. Among these biomarkers, 6 biomarkers (CD5, CCL23, CST5, IL-10RB, PD-L1, TNFRSF9) were inversely linked to eGFR in both diabetes types. In recent-onset type 1 and type 2 diabetes, several biomarkers of inflammation correlate with a lower baseline eGFR but do not correlate with loss of kidney function within the first 5 years after diagnosis of diabetes.