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Biomarkers of exposure among U.S. adult cigar smokers: Population Assessment of Tobacco and Health (PATH) study Wave 1 (2013–2014)

Cancer Epidemiology, Biomarkers & Prevention Apr 25, 2019

Chang CM, et al. - Researchers used Wave 1 urinary biomarker data from 5,604 adults in the Population Assessment of Tobacco and Health study in order to compare biomarkers of nicotine and tobacco toxicants among cigar smokers and other groups. Compared with every day cigar-only smokers, lower biomarker concentrations were detected among cigar-only smokers who partook only some days, but the levels were higher than never-users. In comparison to every day cigarette-only (n=2,217) and dual cigar/cigarette smokers (n=601), lower TNE-2 (cotinine+trans-3′-hydroxycotinine) was detected in every day cigar-only smokers (n=61). These groups demonstrated comparable various biomarkers, including NNAL (NNK metabolite) and CYMA (metabolite of acrylonitrile). Higher biomarker concentrations were detected in every day filtered cigar-only (n=7) smokers vs every day traditional cigar-only smokers (n=12) and cigarillo-only smokers (n=24), according to exploratory analyses. They found a similarity between every day smokers of each cigar type and exclusive cigarette smokers. Higher concentrations were reported for some biomarkers, especially for every day filtered cigar-only smokers.

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