Jaques DA, et al. - Considering the poor efficacy of serum creatinine as a marker of renal function in cirrhotic patients, researchers investigated the utility of several biomarkers in this context. They performed a prospective study in hospitalized patients with decompensated cirrhosis and identified early measurement of renal biomarkers as valuable in providing information on Acute kidney injury (AKI) etiology. Analyzing 105 patients, of which 55 had AKI, they noted Serum creatinine (SCr), Cystatin C (CystC), NGAL (plasma and urinary), urinary sodium and renal resistive index at inclusion to have an independent association with the presence of AKI. Measurement of SCr, CystC and plasma NGAL were predictive of the subsequent development of AKI. Hence using these markers, improvement in AKI diagnosis and prognosis could be achieved