Marcovecchio ML, Colombo M, Dalton RN, et al. - Researchers investigated biomarkers of renal disease among adolescents suffering from type 1 diabetes (T1D), and compared results in adults with T1D. In 553 adolescents recruited to the Adolescent Type 1 Diabetes Cardiorenal Intervention Trial, measurements of 25 serum biomarkers were obtained. Experts evaluated link with baseline and final estimated glomerular filtration rate (eGFR), rapid decliner and rapid increaser phenotypes (eGFR slopes <‐3 and >3ml/min/1.73m²/year, respectively) and albumin‐creatinine ratio. They used 859 adults (age: 55.5[46.1, 64.4) years) from the Scottish Diabetes Research Network Type 1 Bioresource, for comparison. Findings showed that osteopontin was identified as the most consistent biomarker related to prospective alterations in eGFR in this young group with T1D and high rates of hyperfiltration. A link of fibroblast growth factor‐23 with eGFR rises was identified, whereas trefoil factor‐3, cystatin C and beta‐2 microglobulin were found to be only related to baseline eGFR.