Araújo AM, et al. - Researchers conducted a cross sectional study to estimate propofol dose in adult and older patients (n = 40) with BMI equal to or lower than 35 kg/m² based on size descriptors measured by bioelectrical impedance analysis (BIA). During the preoperative evaluation, BIA and Clinical Frail Scale scoring were conducted. Weight-based reduction of propofol is suitable in older patients for the fixed infusion rate of propofol (2000 mg/h) used in the present study. Nevertheless, in predicting the dose of propofol induction in these patients, fat free mass was not seen to be more effective than total body weight. Guiding the induction dose of propofol based on the baseline frailty score should also be considered in estimating individualized dosage profiles. To evaluate frailty in older patients, determination of phase angle value seems to be an easy and reliable tool.