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Biliary-enteric drainage vs primary liver transplant as initial treatment for children with biliary atresia

JAMA Jan 22, 2019

LeeVan E, et al. - In this cohort study of 626 infants with biliary atresia, researchers compared the survival of patients with biliary atresia initially treated with biliary-enteric drainage (BED) with patients who underwent primary liver transplant (pLT). Using deidentified records from the California Office of Statewide Health Planning and Development database, they performed a cohort study of patients with biliary atresia (n=1,252) between January 1, 1990, through December 31, 2015. A substantially higher risk of mortality was evident for patients requiring salvage liver transplant than patients who received pLT. Findings revealed that patients undergoing pLT experienced superior long-term survival compared to patients undergoing BED therapy.
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