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Bilateral native nephrectomy to reduce oxalate stores in children at the time of combined liver–kidney transplantation for primary hyperoxaluria type 1

Pediatric Nephrology Mar 23, 2018

Lee E, et al. - Herein, researchers reported their experience of managing children with primary hyperoxaluria type-1 (PH-1) and end-stage renal disease (ESRD) on hemodialysis (HD) who underwent combined liver–kidney transplant (CLKT) at their institution from 2005 to 2015. CLKT continued to be the definitive treatment for PH-1, while bilateral native nephrectomy at the time of transplant was shown to be effective at attenuating postoperative oxalate stores and may mitigate damage to the renal allograft.
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