Ribera A, et al. - The authors performed this study to validate an easy-to-use method to guide beta-lactams dosage in continuous infusion (CI) (formula: daily dose = 24 h × beta-lactam clearance × target “steady-state” concentration) for Gram-negative bacilli osteoarticular infections. Based on the observations, they concluded that in clinical practice, the formula could be useful for planning the initial dosage of beta-lactams in CI, while awaiting a systematic therapeutic drug monitoring. In CI, using beta-lactams was safe.