Kemmerer EJ, et al. - Researchers performed a propensity score weighted, population-based analysis to determine the impact of external beam radiotherapy (EBRT) on cancer-specific survival (CSS) for patients with localized extraskeletal myxoid chondrosarcoma (EMC) identified using the Surveillance, Epidemiology, and End Results database (1973 to 2012). CSS as primary endpoint was assessed for cases of localized EMC arising from soft connective tissues of the trunk and extremities treated with surgery and/or EBRT. They utilized inverse probability treatment weighting and survival analysis was carried out. The findings demonstrated a CSS benefit related to the receipt of EBRT in patients with localized EMC. In these patients, treatment with aggressive local therapy, including EBRT, was recommended to be considered.