Zhang J, Cao J, Zhang Y, et al. - Using a nested case-control design involving 599 first stroke cases and 599 matched controls, researchers analyzed the relationship between baseline plasma zinc with the risk of the first stroke, and examined any possible effect modifiers in hypertensive patients. The study population was drawn from the China Stroke Primary Prevention Trial. The investigators noted a significantly lower risk of first hemorrhagic stroke in patients with plasma zinc ≥ 106.9 μg/dL vs those with baseline plasma zinc < 106.9 μg/dL (median). A significant inverse connection was observed between plasma zinc and first hemorrhagic stroke in this study population. However, no significant link was found between plasma zinc and first ischemic stroke.