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Baseline plasma fibrinogen is associated with haemoglobin A1c and 2-year major adverse cardiovascular events following percutaneous coronary intervention in patients with acute coronary syndrome: A single-centre, prospective cohort study

Cardiovascular Diabetology Apr 28, 2019

Zhang L, et al. - In this study from China, which included 411 patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI), researchers investigated the links between fibrinogen (FIB), glucose metabolism (hemoglobin A1c [HbA1c] and fasting blood glucose [FBG]), and major adverse cardiovascular events (MACEs) post-PCI in diabetes mellitus (DM), non-DM, or whole patients with ACS. In whole and DM populations with ACS, a positive association of FIB with glucose metabolism (HbA1c and FBG) was evident. Findings also suggested a possible significance of elevated baseline FIB levels as an independent predictor of MACEs post-PCI, particularly among those with DM. Baseline FIB levels could no longer predict MACEs, however, as the follow-up period increased.

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