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Barriers to hepatitis C direct‐acting antiviral therapy among HIV/HCV‐coinfected persons

Journal of Gastroenterology and Hepatology Aug 30, 2020

Jatt LP, Gandhi MM, Guo R, et al. - In HIV/HCV patients during the first few years of DAA availability in the United States, researchers analyzed the frequency of and potential barriers to getting a prescription for direct‐acting antivirals (DAA). They identified all HCV viremic HIV‐infected patients in care at AHF Healthcare Centers January 2015‐August 2017 via the AIDS Healthcare Foundation (AHF) electronic medical record system; according to the receipt of a DAA prescription, they compared features. Out of 826 qualifying participants, 355 (43%) got a DAA prescription. Out of those not prescribed a DAA, 301 (64%) had well‐controlled HIV (HIV RNA ≤ 200 copies/mL). Being on a select ARV regimen, substance use, a lack of HIV suppression, and kidney disease were all impediments to receiving a DAA prescription in the early interferon‐free DAA era, however even those with HIV suppression were not prescribed DAAs.

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