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Axitinib in combination with pembrolizumab in patients with advanced renal cell cancer: A non-randomised, open-label, dose-finding, and dose-expansion phase 1b trial

The Lancet Oncology Feb 15, 2018

Atkins MB, et al. - Axitinib, a more selective VEGF inhibitor than others previously tested, was hypothesized to combine safely with pembrolizumab (anti-PD-1) and yield anti-tumour activity in patients with treatment-naive advanced renal cell carcinoma. Axitinib + pembrolizumab was tolerable and showed promising antitumour activity in patients with treatment-naive advanced renal cell carcinoma.

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