Axial involvement in patients with early peripheral spondyloarthritis: A prospective MRI study of sacroiliac joints and spine
Annals of Rheumatic Diseases Nov 01, 2020
Renson T, Carron P, De Craemer AS, et al. - This study was attempted to evaluate axial involvement on MRI in early peripheral spondyloarthritis (pSpA) and to assess if axial inflammation predicts relapse on treatment withdrawal. Researchers recruited a total of 56 individuals with early, active, newly diagnosed pSpA who had undergone MRI of the sacroiliac joints (SIJs) and spine prior to golimumab initiation. It was shown that a surprisingly high prevalence of sacroiliitis on MRI was observed in patients with early pSpA; SPARCC scores reduced significantly on tumour necrosis factor inhibition. The data exhibited that residual inflammation on MRI was not predictive of relapse of peripheral manifestations. They did not detect relevant inflammatory spinal involvement. The data imply a higher inflammatory burden in patients with early pSpA than anticipated.
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