Wang K, et al. - This study incorporated an inquiry of the sensitivity and specificity of an automated algorithm for detecting referral-warranted diabetic retinopathy (DR) on Optos ultrawidefield (UWF) pseudocolour images. An automated algorithm revealed diabetic retinopathy (DR) lesions from Optos pseudocolour UWF images. Images were classified as referral-warranted DR with a high degree of sensitivity and moderate specificity. Automated analysis of UWF images could be valuable for the DR screening programmes. It possibly facilitated a more complete and accurate disease staging.