Hoang-Thi TN, et al. - In this retrospective study, researchers developed an automated computed tomography (CT) score based on the CT quantification of high-attenuating lung structures, in order to provide a quantitative assessment of lung structural abnormalities in 62 adult (≥18 years) PCD patients who had both chest CT and spirometry within a 6-month period. It was noted that mean lung density (MLD) + 1SD (standard deviation) offered the best correlations with both forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). For evaluation of disease severity in the clinic and in clinical trials, automated CT scoring of lung structural abnormalities lung in primary ciliary dyskinesia is feasible and might prove useful.