Niechcial E, et al. - The authors designed this work to assess the prevalence of ZnT8-ab (Autoantibodies to zinc transporter-8) and its correlation to other autoimmune markers and diabetic ketoacidosis occurrence in children and adults with T1DM (Type 1 diabetes mellitus) onset. They observed a greater risk of ketoacidosis at the diagnosis of diabetes among children. While adults frequently showed a higher titer of GAD-ab (Glutamic acid decarboxylase autoantibodies), children commonly showed ZnT8-ab and IA2-ab (Protein tyrosine phosphatase autoantibodies). Here, ZnT8-ab were found to be linked with more acute diabetes onset.