Conceição MS, et al. - In the present study, researchers circumscribed the respective chronic (ie, 8 weeks) functional, morphological and molecular responses of endurance training performed with blood flow restriction (ET-BFR) training compared to conventional, unrestricted resistance training (RT) and endurance training (ET) via randomly assigning 30 healthy young men. The findings suggested that 8 weeks of ET-BFR can increase muscle strength and induce similar muscle hypertrophy responses to RT. On the other hand, V˙O2max responses also increased post-intervention even with a significantly lower work load compared to ET. The results obtained from the study provide new insight to some of the molecular mechanisms mediating adaptation responses with ET-BFR and the potential for this training protocol to improve muscle and cardiorespiratory capacity.