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Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: A population-level modelling analysis

The Lancet Infectious Diseases Jan 18, 2019

Cassini A, et al. - Researchers performed the first study estimating the burden of five types of infection caused by antibiotic-resistant bacteria expressed in disability-adjusted life-years (DALYs) in countries of the EU and European Economic Area (EEA) in 2015. From European Antimicrobial Resistance Surveillance Network (EARS-Net) 2015 data, 671 689 infections with antibiotic-resistant bacteria were identified. Of these, 63·5% were associated with health care. These infections accounted for an estimated 33,110 attributable deaths and 874,541 DALYs indicating a substantial burden of these infections in the EU and EEA compared to other infectious diseases. Findings revealed that infections with antibiotic-resistant bacteria affect all age groups, however, infants (aged <1 year) display the highest burden. They observed a great variation in the contribution of various antibiotic-resistant bacteria to the overall burden between countries highlighting the need for prevention and control strategies that are tailored to the needs of each country in the EU and EEA.
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