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Atopic dermatitis among children and adolescents in the Arctic region – A systematic review and meta‐analysis

Journal of the European Academy of Dermatology and Venereology Apr 13, 2021

Andersson AM, Halling AS, Loft N, et al. - The selection of the studies was carried out using PubMed, Embase and Web of Science to investigate the prevalence, clinical manifestations and risk factors for atopic dermatitis (AD) among children and adolescents in the Arctic. Between 1990 to 2020, all studies published with epidemiologic data on AD in children and adolescents in the Arctic region were included. The authors found 21 studies involving 31,403 people from 8 different Arctic regions. Data reported that the cumulative incidence of AD was 23% and 1‐year prevalence was 19%. The prevalence of AD was higher in the Arctic parts of Scandinavia and lower in Greenland and Russia. According to this systematic review and meta‐analysis, AD is common in the Arctic, but it varies by region and race. Indigenous children in less urbanized countries seem to have a slightly lower risk of AD. Future research should confirm this and investigate whether the correlation is due to behavioral differences or a genetic signature.

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