Urowitz MB, et al. - Via analyzing inception patients who entered the University of Toronto Lupus Clinic between 1975 and 1987 followed to 1992 (Cohort 1), and between 1999 and 2011 followed to 2016 (Cohort 2), researchers ascertained the impact of early recognition and therapy for both classic risk factors for atherosclerotic vascular events (AVE) and for SLE, on the burden of AVE in SLE in recent decades. SLE disease activity and therapy as well as hypertension, hypercholesterolemia, hyperglycemia, and smoking have been evaluated. Of the 234 individuals in Cohort 1, 26 individuals had an AVE vs 10 of 262 individuals in Cohort 2. In the modern era, the occurrence of AVE throughout SLE has decreased largely due to more effective management of risk factors for classic coronary artery and SLE.