Sahoo S, Derwin KA, Zajichek A, et al. - Researchers assumed that worse mental health status evaluated by VR-12 MCS, glenoid bone loss, and increasing rotator cuff tear severity would be correlated with lower preoperative total PENN Shoulder Score (PSS) and its pain, function, and satisfaction subscores. They prospectively distinguished 12 patient factors and four disease-specific factors as possible statistical predictors for preoperative PROMs in patients undergoing primary shoulder arthroplasty at a single institution over a 3-year period. They applied multivariable statistical modeling and Akaike’s Information Criterion (AIC) comparisons to evaluate the unique correlations with, and relative importance of, these factors in accounting for variation in preoperative PSS and its subscores. Twelve surgeons performed 788 cases, with a preoperative median total PSS of 31 (pain 10, function 18, satisfaction 1). The data indicated that patient gender, years of education, and preoperative opioid use were most prominently associated with preoperative PROMs in patients undergoing shoulder arthroplasty in addition to mental health status and rotator cuff tear status. Future trials are required to evaluate whether these factors will also prognosticate postoperative PROMs.