Ferguson TF, Rosen E, Carr R, et al. - Among people living with HIV (PLWH) examined in this cross-sectional analysis of the New Orleans Alcohol Use in HIV (NOAH) study, researchers evaluated if current and lifetime alcohol use in these people is related to greater liver disease. They also investigated how this link could be modified by hepatitis C-viral (HCV) co-infection (HIV/HCV+). The study sample (n = 353) was predominantly comprised of male (69%) and black (84%) individuals, with a mean age of 48.3 ± 10 years. The researchers identified a significant link of Lifetime Drinking History (LDH) with advanced liver fibrosis only in HIV/HCV+ participants with an LDH of 100–600 kg. A higher prevalence of intermediate and advanced liver disease markers was noted in HIV/HCV+ participants vs HIV/HCV−. The most strong link with hazardous drinking (≥40[women]/60[men] grams/day) and PEth ≥400 ng/ml was shown by advanced markers of liver disease. Findings were suggestive of a greater link of current alcohol use with the liver disease compared with lifetime alcohol use, which differed by HCV status. The significance of decreasing alcohol use in PLWH to reduce the risk of liver disease and fibrosis was emphasized by the findings.