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Associations of gout and baseline serum urate level with cardiovascular outcomes: Analysis of the Coronary Disease Cohort Study

Arthritis & Rheumatology Sep 07, 2019

Stamp LK, et al. - In this investigation involving 1,514 candidates, researchers ascertained if gout and serum urate (SU) levels were correlated with increased risk of death, time to first readmission for any cardiovascular event, or incident heart failure in people with cardiovascular disease. The Coronary Disease Cohort Study involved individuals with acute coronary syndrome (ACS). Clinical data were gathered at the index hospital admission from the medical records and postdischarge clinical, echocardiographic and biochemical data were gathered. Fifty-three of 160 participants with gout and 298 of 1,354 candidates without gout died during the follow-up period. Patients with and without gout had similar survival post-ACS. An increased risk of readmission for heart failure and higher length of stay for people with gout were noted. In parallel with increases in SU levels, the risk of these events increases.
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