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Associations of general obesity and central obesity with the risk of hepatocellular carcinoma in a Korean population: A national population‐based cohort study

International Journal of Cancer Oct 30, 2020

Hwang S, Park YM, Han KD, et al. - Since many prior studies have shown a link between hepatocellular carcinoma (HCC) and general obesity, but data specifically in Asian populations is sparse, researchers explored how the risk of HCC correlates with both WC (representing central obesity) and BMI (representing general obesity) in Korea. In total, 10,505,818 candidates who got National Health Insurance Service (NHIS) health checkups in 2009 were screened for study eligibility; there were 26,979 cases of HCC during the 7.3 years of mean follow‐up. General obesity increased the risk of HCC vs those whose BMI is within the normal range. Central obesity was also associated with a higher risk of HCC. The results also show that when general obesity is combined with central obesity, the risk of HCC increases even more. In addition, central obesity is associated with the risk of HCC, irrespective of general obesity.

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