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Associations of cutaneous and extracutaneous infections with hidradenitis suppurativa in U.S. children and adults

British Journal of Dermatology Jul 31, 2019

Lee HH, et al. - Via analyzing data from the 2002-2012 National Inpatient Sample, including a 20% sample of US hospitalizations (n = 87,053,155), researchers determined if there is a correlation between hidradenitis suppurativa (HS) and cutaneous and extracutaneous infections and related results. Infection prevalence in adults and children with vs those without HS was higher. In general, HS patients had a higher prevalence of infections (excluding cellulitis and erysipelas) vs those with psoriasis but a lower prevalence vs those with atopic dermatitis. It was noted that patients with comorbid cancer, HIV, cardiometabolic, autoimmune or mental health diagnoses or acne were even more likely to be infected. The authors concluded that increased acute and chronic, cutaneous, extracutaneous and systemic infections were seen among adults and children with HS, and these were linked to increased death and cost.

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