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Associations of body fat and skeletal muscle with hypertension

The Journal of Clinical Hypertension Dec 13, 2018

Han TS, et al. - Researchers ascertained the association of body fat and skeletal muscle (SM) with hypertension in 2,595 non-insulin- and 536 insulin-treated diabetic patients. They used Scottish Health Surveys (2003, 2008-2011) and Health Surveys for England (2003-2006, 2008-2013) to extract population-based data from 22,591 men (mean age: 51.6 ± 16.9 years) and 27,845 nonpregnant women (50.6 ± 16.9 years). They found that patients with undetected, controlled, uncontrolled, and untreated hypertension had a significantly higher percent body fat (BF%) and percent SM lower (P < 0.001), compared with normotensive individuals. A 2.3-fold-2.6-fold greater risk of hypertension was observed in diabetics vs non-diabetics, independent of confounding factors and BF% or SM%. Hypertension displayed higher associations with BF% than those with body mass index (BMI). Based on the findings, result analysis from health surveys should be done by taking into account both BF and SM, rather than relying on BMI which does not discriminate between the two.
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